💿🐜 Antkeeper source code https://antkeeper.com
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/*
* Copyright (C) 2021 Christopher J. Howard
*
* This file is part of Antkeeper source code.
*
* Antkeeper source code is free software: you can redistribute it and/or modify
* it under the terms of the GNU General Public License as published by
* the Free Software Foundation, either version 3 of the License, or
* (at your option) any later version.
*
* Antkeeper source code is distributed in the hope that it will be useful,
* but WITHOUT ANY WARRANTY; without even the implied warranty of
* MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
* GNU General Public License for more details.
*
* You should have received a copy of the GNU General Public License
* along with Antkeeper source code. If not, see <http://www.gnu.org/licenses/>.
*/
#include "base.hpp"
namespace genetics {
namespace base {
/**
* Decodes an IUPAC degenerate base symbol into a bit mask representing the possible bases represented by the symbol.
*
* @param symbol IUPAC degenerate base symbol.
* @return Bit mask representing the possible bases represented by the symbol.
*/
static inline unsigned char decode(char symbol)
{
static constexpr unsigned char bases[25] =
{
0b0001, // A
0b1110, // B
0b0010, // C
0b1101, // D
0, // E
0, // F
0b0100, // G
0b1011, // H
0, // I
0, // J
0b1100, // K
0, // L
0b0011, // M
0b1111, // N
0, // O
0, // P
0, // Q
0b0101, // R
0b0110, // S
0b1000, // T
0b1000, // U
0b0111, // V
0b1001, // W
0, // X
0b1010, // Y
};
return (symbol < 'A' || symbol >= 'Z') ? 0 : bases[symbol - 'A'];
}
int compare(char a, char b)
{
static constexpr int popcount[16] =
{
0, 1, 1, 2, 1, 2, 2, 3, 1, 2, 2, 3, 2, 3, 3, 4
};
return popcount[decode(a) & decode(b)];
}
char transcribe(char symbol)
{
return (symbol == 'T') ? 'U' : (symbol == 'U') ? 'T' : symbol;
}
namespace dna
{
char complement(char symbol)
{
static constexpr char* complements = "TVGHZZCDZZMZKNZZZYSAABWZR";
return (symbol < 'A' || symbol >= 'Z') ? 'Z' : complements[symbol - 'A'];
}
}
namespace rna
{
char complement(char symbol)
{
static constexpr char* complements = "UVGHZZCDZZMZKNZZZYSAABWZR";
return (symbol < 'A' || symbol >= 'Z') ? 'Z' : complements[symbol - 'A'];
}
}
} // namespace base
} // namespace genetics